Update: Marty Makary has resigned.

According to an administration official who spoke with Politico, Marty Makary, the Food and Drug Administration commissioner, is set to resign on Tuesday.

Makary led the agency for 13 months.

Last week, The Gateway Pundit reported that President Trump signaled that he signed off on a plan to fire Makary.

On Friday, The Washington Post, New York Times, and The Wall Street Journal reported that Makary was going to be fired because he isn’t getting along with other health department officials.

The administration official who spoke with Politico said that Kyle Diamantas, who previously served as the agency’s top food official, will lead the FDA in an acting capacity.

Per Politico:

The administration official said that while the White House had to sign off on the decision, HHS Secretary Robert F. Kennedy Jr. made the call.

“It was really Secretary Kennedy himself who made this decision,” the administration official said.

Still, as of Tuesday morning, Makary had public appearances scheduled throughout the week and was quoted in agency press releases. FDA staff told POLITICO that leadership was working this week as if nothing was amiss in the commissioner’s office.

Prolife groups and Republican lawmakers have criticized Makary for not restricting access to Mifepristone more aggressively and for being too moderate on the issue, frustrating pro-life factions in the administration.

Watch:

BREAKING: FDA Commissioner Marty Makary has RESIGNED, per AP

Makary reportedly was not aligned with President Trump or HHS Secretary Kennedy on a myriad of issues.

Who should take his place and become the new FDA Commissioner? pic.twitter.com/XiCMIJOOCv

— Nick Sortor (@nicksortor) May 12, 2026

President Trump responded to Makary’s resignation.

JUST IN: President Trump responds to Dr. Marty Makary resigning from his post as FDA Commissioner:

“Everybody wants that job. It’s a very important job… He was having some difficulties, he’s a great doctor and he was having some difficulties. But he’s going to go on and he’s… pic.twitter.com/SHG3eUyE81

— Fox News (@FoxNews) May 12, 2026

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